Anticholinesterase activity of 7-methoxyflavones isolated from Kaempferia parviflora.

  title={Anticholinesterase activity of 7-methoxyflavones isolated from Kaempferia parviflora.},
  author={Pattara Sawasdee and Chalisa Sabphon and Duangporn Sitthiwongwanit and Udom Kokpol},
  journal={Phytotherapy research : PTR},
  volume={23 12},
The rhizome of Kaempferia parviflora or kra-chai-dum (in Thai) is used traditionally as a folk medicine. The preliminary cholinesterase inhibitory screening of this plant extract exhibited significant acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities. Thirteen known methoxyflavones (1-13) were isolated and their structures were completely elucidated based on NMR analysis and compared with literature reports. Minor compounds 12-13 were reported for the first time… CONTINUE READING
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