Anticholinergic toxicity associated with lupin seed ingestion: case report

@article{Grande2004AnticholinergicTA,
  title={Anticholinergic toxicity associated with lupin seed ingestion: case report},
  author={A. Di Grande and R. Paradiso and Salvatore Amico and Giovanni Fulco and Bruno Fantauzza and Paola Noto},
  journal={European Journal of Emergency Medicine},
  year={2004},
  volume={11},
  pages={119-120}
}
We describe a case of acute poisoning in a 51-year-old female patient who presented to the Emergency Department with weakness, anxiety, dry mouth, bilateral mydriasis and lid drop. In differential diagnosis, botulism, Guillain–Barré syndrome and myasthenia gravis were considered, as well as cerebral haematoma because of a cranial injury a week before. Symptoms, which resolved within 12 h without any therapy, were instead related to the ingestion of lupin seeds. 
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19 Citations
Background Citations
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19 Citations

Anticholinergic Toxicity Associated with Lupine Seeds Ingestion—A Case Report
TLDR
A 40-year old woman who presented with blurry vision, nausea, abdominal pain, dizziness, disorientation, and severe mouth dryness for one hour prior to presentation was admitted for observation for 24 hours and her symptoms resolved spontaneously.
Bitter lupine beans ingestion in a child: a disregarded cause of acute anticholinergic toxicity
TLDR
A 6-year-old girl brought to the emergency department for the sudden onset of anticholinergic syndrome after the ingestion of a few home-made partially debittered lupine beans complained of blurry vision, headache, photophobia and nausea.
Acute Bilateral Fixed Mydriasis Caused by Lupini Bean Intoxication.
Anticholinergic Syndrome in Response to Lupin Seed Toxicity
TLDR
A case of anticholinergic toxicity in a patient who ingested improperly prepared lupin seeds is described and the importance of taking patient herbal and food consumption into account in the differential diagnosis of toxic syndromes is highlighted.
Anticholinergics Syndrome Related to Plants and Herbs
TLDR
Plant tropane alkaloids – atropine, scopolamine and hyoscyamine – are the common causes of this toxidrome when they enter the human body through GI absorption and/or skin contact.
Two cases of anticholinergic syndrome associated with consumption of bitter lupin flour
TLDR
The addition of sweet lupin flour to bread has been shown to reduce its glycaemic index, reduce energy intake and increase satiety of study participants compared with those who consumed standard white bread, and the addition ofsweet lupIn flour to sausages was shown to decrease fat intake and increased satiety in study participants when compared withThose who consumed full-fat sausage.
Low-toxicity ingestions
Handbook of Poisonous and Injurious Plants
TLDR
A glossary ofBotanical Nomenclature and Glossary of Botanical Terms, including definitions ofPoisons, Poisoning Syndromes, and Their Clinical Management.
Evaluation of total quinolizidine alkaloids content in lupin flours, lupin-based ingredients, and foods.
TLDR
The QA contents were particularly low in protein isolates and in foods containing these ingredients, indicating that their use is a very effective tool for keeping low the daily intake of QAs.
Scientific opinion on the risks for animal and human health related to the presence of quinolizidine alkaloids in feed and food, in particular in lupins and lupin‐derived products
TLDR
This risk assessment is limited to QAs occurring in Lupinus species/varieties relevant for animal and human consumption in Europe, and the CONTAM Panel considers the risk for adverse effects to be low.
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