Anticholinergic Toxicity Associated with Lupine Seeds Ingestion—A Case Report

@inproceedings{AlAbdouh2020AnticholinergicTA,
  title={Anticholinergic Toxicity Associated with Lupine Seeds Ingestion—A Case Report},
  author={Ahmad Al-Abdouh and Hamzeh Mohammad Alrawashdeh and Ahmad Taha Khalaf and Ibrahim AlNawaiseh},
  year={2020}
}
Lupine, a member of the legume family, is also known as lupines in the USA and as Turmus in the Middle East. Lupine seeds are consumed as an appetizer and in herbal therapy for diabetes mellitus in the Middle East. Quinolizidine alkaloids are found in various plants belonging to the Lupinus genus although the nature and level of these alkaloids are highly variable between species; these compounds are known to cause anticholinergic symptoms. We present a case for a 40-year old woman who… 
1 Citations
Greener Strategy for Lupanine Purification from Lupin Bean Wastewaters Using a Molecularly Imprinted Polymer.
Lupanine is an alkaloid used in the pharma industry as a building block or precursor in the synthesis of sparteine and also explored for drug synthesis in the pharma industry as a chiral selector.

References

SHOWING 1-10 OF 22 REFERENCES
Two cases of anticholinergic syndrome associated with consumption of bitter lupin flour
TLDR
The addition of sweet lupin flour to bread has been shown to reduce its glycaemic index, reduce energy intake and increase satiety of study participants compared with those who consumed standard white bread, and the addition ofsweet lupIn flour to sausages was shown to decrease fat intake and increased satiety in study participants when compared withThose who consumed full-fat sausage.
Bitter lupine beans ingestion in a child: a disregarded cause of acute anticholinergic toxicity
TLDR
A 6-year-old girl brought to the emergency department for the sudden onset of anticholinergic syndrome after the ingestion of a few home-made partially debittered lupine beans complained of blurry vision, headache, photophobia and nausea.
Anticholinergic toxicity associated with lupin seed ingestion: case report
TLDR
A case of acute poisoning in a 51-year-old female patient who presented to the Emergency Department with weakness, anxiety, dry mouth, bilateral mydriasis and lid drop was instead related to the ingestion of lupin seeds.
Disposition of lupanine and 13-hydroxylupanine in man.
TLDR
Overall, the finding of a high urinary recovery of unchanged lupanine or 13-hydroxyl upanine together with similar t1/2s for both alkaloids in EM and PM CYP2D6 phenotypes suggests that clinical toxicity is unlikely to result from the use of lupin seed in footstuffs.
Dilated pupils, dry mouth and dizziness - a case study.
TLDR
Cardiovascular, respiratory, abdominal and neurological examinations were normal, and Electrocardiogram showed normal sinus rhythm with a rate of 98 bpm.
[The effects of a dietary fiber (white lupine bran) in the treatment of non-insulin-dependent diabetes].
TLDR
It is concluded that dietary fiber intake is low in patients but a supplement of 10 to 20 g of this particular fiber did not improve metabolic control.
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