Anticancer therapy targeting the apoptotic pathway.

@article{Hu2003AnticancerTT,
  title={Anticancer therapy targeting the apoptotic pathway.},
  author={Wei Hu and John J. Kavanagh},
  journal={The Lancet. Oncology},
  year={2003},
  volume={4 12},
  pages={721-9}
}
Apoptosis, or programmed cell death, has an essential role in controlling cell number in many developmental and physiological settings and in chemotherapy-induced tumour-cell killing. It is a genetically regulated biological process, guided by the ratio of proapoptotic and antiapoptotic proteins. Recently, inducers of apoptosis have been used in cancer therapy. Several studies have attempted to induce apoptosis by triggering the tumour-necrosis-factor-related apoptosis-inducing ligand receptor… CONTINUE READING

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