Anticancer effects of marine carotenoids, fucoxanthin and its deacetylated product, fucoxanthinol, on osteosarcoma.

@article{Rokkaku2013AnticancerEO,
  title={Anticancer effects of marine carotenoids, fucoxanthin and its deacetylated product, fucoxanthinol, on osteosarcoma.},
  author={Takayoshi Rokkaku and Ryuichiro Kimura and C. Millikin Ishikawa and Takeshi Yasumoto and Masachika Senba and Fuminori Kanaya and Naoki Mori},
  journal={International journal of oncology},
  year={2013},
  volume={43 4},
  pages={1176-86}
}
Survival of osteosarcoma patients hinges on prevention or treatment of recurrent and metastatic lesions. Therefore, novel chemotherapeutics for more effective treatment and prevention of this disease are required. Carotenoids are natural pigments and exhibit various biological functions. We evaluated the anti-osteosarcoma properties of several carotenoids. Among carotenoids, fucoxanthin and its metabolite fucoxanthinol, inhibited the cell viability of osteosarcoma cell lines. Fucoxanthinol… CONTINUE READING