Corpus ID: 51619341

Anticancer effects of Rosmarinic acid in OVCAR-3 ovarian cancer cells are mediated via induction of apoptosis, suppression of cell migration and modulation of lncRNA MALAT-1 expression.

@article{Zhang2018AnticancerEO,
  title={Anticancer effects of Rosmarinic acid in OVCAR-3 ovarian cancer cells are mediated via induction of apoptosis, suppression of cell migration and modulation of lncRNA MALAT-1 expression.},
  author={Yan E. Zhang and M. Hu and Liu Liu and Xiaoling Cheng and J. Cai and J. Zhou and Tao Wang},
  journal={Journal of B.U.ON. : official journal of the Balkan Union of Oncology},
  year={2018},
  volume={23 3},
  pages={
          763-768
        }
}
  • Yan E. Zhang, M. Hu, +4 authors Tao Wang
  • Published 2018
  • Chemistry, Medicine
  • Journal of B.U.ON. : official journal of the Balkan Union of Oncology
PURPOSE The main objective of the present research work was to study the anticancer properties of rosmarinic acid in OVCAR-3 human ovarian cancer cells and also to evaluate its effects on apoptosis induction, cancer cell migration and modulation of lncRNA MALAT-1 expression. METHODS MTT assay was used to study the effects of the agent on OVCAR-3 cell viability, while inverted phase contrast microscopy and fluorescence microscopy were used to study the effects on cell morphology. Scanning… Expand
Micromeria fruticosa Induces Cell Cycle Arrest and Apoptosis in Breast and Colorectal Cancer Cells
Reflections on the Role of Malat1 in Gynecological Cancer
Emerging roles of long noncoding RNAs in chemoresistance of pancreatic cancer.
LncRNAs in ovarian cancer.
Network Pharmacology and Molecular Docking Suggest the Mechanism for Biological Activity of Rosmarinic Acid

References

SHOWING 1-10 OF 17 REFERENCES
Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines.
Anticancer effects of Alpinia pricei Hayata roots.
Evasion of Apoptosis as a Cellular Stress Response in Cancer
  • S. Fulda
  • Medicine
  • International journal of cell biology
  • 2010
Targeted therapy for epithelial ovarian cancer: Current status and future prospects
  • H. See, W. Hu, R. Bast
  • Medicine
  • International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • 2003
Herbal medicine in the treatment of cancer.
Plants as a source of therapeutic and health products.
Plants as a source of anti-cancer agents.
Plant-derived triterpenoids as potential antineoplastic agents.
...
1
2
...