Anticancer drug vinblastine sulphate induces transient morphological changes on the olfactory mucosa of the rabbit.

@article{Kavoi2012AnticancerDV,
  title={Anticancer drug vinblastine sulphate induces transient morphological changes on the olfactory mucosa of the rabbit.},
  author={B M Kavoi and Andrew Ndegwa Makanya and Stephen Gitahi Kiama},
  journal={Anatomia, histologia, embryologia},
  year={2012},
  volume={41 5},
  pages={374-87}
}
Vinblastine sulphate (VBS) is an anticancer drug that acts by disrupting microtubule dynamics of highly mitotic tissue cells. The consequences of VBS on the olfactory mucosa (OM), a tissue with high mitotic numbers, are not clearly understood. We used qualitative and quantitative methods to determine the structural changes that may be produced on the rabbit… CONTINUE READING