Anticancer drug-induced kidney disorders.

@article{Kintzel2001AnticancerDK,
  title={Anticancer drug-induced kidney disorders.},
  author={Polly E. Kintzel},
  journal={Drug safety},
  year={2001},
  volume={24 1},
  pages={
          19-38
        }
}
Nephrotoxicity is an inherent adverse effect of certain anticancer drugs. Renal dysfunction can be categorised as prerenal uraemia, intrinsic damage or postrenal uraemia according to the underlying pathophysiological process. Renal hypoperfusion promulgates prerenal uraemia. Intrinsic renal damage results from prolonged hypoperfusion, exposure to exogenous or endogenous nephrotoxins, renotubular precipitation of xenobiotics or endogenous compounds, renovascular obstruction, glomerular disease… CONTINUE READING

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