Anticancer drug-induced kidney disorders.

  title={Anticancer drug-induced kidney disorders.},
  author={Polly E. Kintzel},
  journal={Drug safety},
  volume={24 1},
Nephrotoxicity is an inherent adverse effect of certain anticancer drugs. Renal dysfunction can be categorised as prerenal uraemia, intrinsic damage or postrenal uraemia according to the underlying pathophysiological process. Renal hypoperfusion promulgates prerenal uraemia. Intrinsic renal damage results from prolonged hypoperfusion, exposure to exogenous or endogenous nephrotoxins, renotubular precipitation of xenobiotics or endogenous compounds, renovascular obstruction, glomerular disease… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 79 extracted citations

Inhibition of COX-2/PGE2 cascade ameliorates cisplatin-induced mesangial cell apoptosis.

American journal of translational research • 2017
View 1 Excerpt

The potential protective role of taurine against 5-fluorouracil-induced nephrotoxicity in adult male rats.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie • 2017
View 1 Excerpt

Similar Papers

Loading similar papers…