Anticancer constituents from the roots of Rubia cordifolia L.

  title={Anticancer constituents from the roots of Rubia cordifolia L.},
  author={Jong Keun Son and Soon Ja Jung and Ji Hyun Jung and Zhe Fang and Chong Soon Lee and Chang Seob Seo and Dong Cheul Moon and Byung Sun Min and Mi Ryeo Kim and Mi Hee Woo},
  journal={Chemical & pharmaceutical bulletin},
  volume={56 2},
Activity-directed isolation of the methylene chloride fraction of the roots of Rubia cordifolia L. resulted in the identification of a new epoxymollugin (3) and eight known compounds (1, 2, 4-9). The structures of the compounds were elucidated from chemical and spectroscopic evidence. In addition, their topoisomerase I and II inhibitory activities and cytotoxicities were measured. 

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