Anticancer activities of tanshinone microemulsion against hepatocellular carcinoma in vitro and in vivo.

Abstract

The natural product tanshinone (Tan) induces apoptosis and differentiation in hepatocellular carcinoma (HCC) cells, but its clinical use is limited by its poor water solubility and the lack of appropriate formulations. In this study, Tan was encapsulated into a microemulsion (ME) composed of phospholipid, ethyl oleate, glycerol and Pluronic F68. The… (More)
DOI: 10.3892/mmr.2012.1129

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