Anticancer activities of harmine by inducing a pro-death autophagy and apoptosis in human gastric cancer cells.

@article{Li2017AnticancerAO,
  title={Anticancer activities of harmine by inducing a pro-death autophagy and apoptosis in human gastric cancer cells.},
  author={Chuan Li and Yihai Wang and Chunhua Wang and Xiaomin Yi and Mingya Li and Xiangjiu He},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2017},
  volume={28},
  pages={
          10-18
        }
}
BACKGROUND Harmine, a β-carboline alkaloid from Peganum harmala, has multiple anti-tumor activities, especially for its folk therapy for digestive system neoplasm. However, the underlying mechanism of harmine on gastric cancer remains unclear. PURPOSE To illuminate the potential anti-tumor activity and mechanism of harmine against gastric cancer cells. METHODS/STUDY DESIGNS The anti-proliferative activity of harmine in vitro was evaluated by MTT assay. The autophagic activity induced by… CONTINUE READING
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