Antibody tests suggest that coronavirus infections vastly exceed official counts
@article{Mallapaty2020AntibodyTS, title={Antibody tests suggest that coronavirus infections vastly exceed official counts}, author={Smriti Mallapaty}, journal={Nature}, year={2020} }
Study estimates a more than 50-fold increase in coronavirus infections compared to official cases, but experts have raised concerns about the reliability of antibody kits. Study estimates a more than 50-fold increase in coronavirus infections compared to official cases, but experts have raised concerns about the reliability of antibody kits.
34 Citations
Estimation Without Representation: Early Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence Studies and the Path Forward
- MedicineThe Journal of infectious diseases
- 2020
This viewpoint discusses the pitfalls that can arise with the use of convenience samples and offers guidance for moving towards more representative and timely population estimates of COVID-19 seroprevalence.
COVID‐19: test, trace and isolate‐new epidemiological data
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In the absence of an efficient drug treatment or a vaccine, the control of the COVID‐19 pandemic relies on classic infection control measures, and better knowledge of the epidemiology of the new coronavirus epidemic is crucial to achieve control at a sustainable cost, and within tolerable restrictions of civil rights.
An investigation of testing capacity for evaluating and modeling the spread of coronavirus disease
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- 2021
Antibody detection assays for COVID‐19 diagnosis: an early overview
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- 2020
The objective of this review is to share the diagnostic performance of various immunological assays reported so far in severe acute respiratory syndrome coronavirus 2 case detection and consolidate the studies related to serological tests in COVID‐19 diagnosis and update the current scenario.
Doing more tests: Next challenge for Covid 19 in India
- SociologyVirusDisease
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In response to Coronavirus 19 pandemic, countries are struggling to contain its spread and save precious human lives, and doing extensive tests would emerge as a major strategy for stopping the progression of the pandemic.
Serum pooling for rapid expansion of anti-SARS-CoV-2 antibody testing capacity
- MedicineTransfusion Clinique et Biologique
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SARS-CoV-2 pandemic: a review of molecular diagnostic tools including sample collection and commercial response with associated advantages and limitations
- BiologyAnalytical and Bioanalytical Chemistry
- 2020
This work puts forth key observations in the functionality of current methods for SARS-CoV-2 diagnostic testing, which include nucleic acid amplification–, CRISPR-, sequencing-, antigen-, and antibody-based detection methods.
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- MedicineApplied microbiology and biotechnology
- 2021
Cross-disciplinary approaches may improve the efficiency of COVID-19 diagnosis by compensating to some extent the limitations encountered by traditional test methods during the CO VID-19 pandemic.
A Serological Snapshot of COVID-19 Initial Stages in Israel by a 6-Plex Antigen Array
- Biology, MedicineMicrobiology spectrum
- 2021
A serological snapshot of Israeli patients and healthy adults in the early months of the COVID-19 pandemic confirmed a very low seroprevalence of anti-SARS-CoV-2 antibodies in the Israeli adult population, and suggested that the presence of low-level cross-reacting antibodies in naive individuals calls for a combined, multiantigen analysis for accurate discrimination between naive and exposed individuals.
Die Prävalenz von SARS-CoV-2-IgG-AK liegt bei 1,2%
- Medicine, BiologyMMW - Fortschritte der Medizin
- 2020
The prevalence of 1.2% of SARS-CoV-2-IgG-antibodies and consequently the rate of infection in asymptomatic outpatients in Northrhine-Westfalia (Germany) is low and the impact of virus neutralisation by antibodies and consequently immunization is the challenge of further investigations.