Antibody testing and RT-PCR results in hepatitis C virus (HCV) infection: HCV-RNA detection in PBMC of plasma viremia-negative HCV-seropositive persons

@article{Caudai1998AntibodyTA,
  title={Antibody testing and RT-PCR results in hepatitis C virus (HCV) infection: HCV-RNA detection in PBMC of plasma viremia-negative HCV-seropositive persons},
  author={Cinzia Caudai and M. G. Padula B. Sc. and I. Bastianoni B. Sc. and D. P.E.ValensinM. and D. V.ShyamalaPh. and D. J.HanPh. and D. C.A.BoggianoM. and D. P.AlmiM.},
  journal={Infection},
  year={1998},
  volume={26},
  pages={151-154}
}
To evaluate the concordance between viremia and antibody testing in hepatitis C virus (HCV) diagnosis, 682 serum or plasma samples collected from patients with known or suspected HCV infection were tested. An overall concordance of 77% between serological and PCR results was found, 5% was RNA positive/antibody negative and 18% antibody positive/RNA negative. The relationship between HCV infection, risk group and clinical diagnosis was studied in 116 patients: the presence of anti-HCV antibody… CONTINUE READING
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