Antibody structure, instability, and formulation.

  title={Antibody structure, instability, and formulation.},
  author={Wenxin Wang and Satish Kumar Singh and David Zeng and Kevin R King and Sandeep Nema},
  journal={Journal of pharmaceutical sciences},
  volume={96 1},
The number of therapeutic monoclonal antibody in development has increased tremendously over the last several years and this trend continues. At present there are more than 23 approved antibodies on the US market and an estimated 200 or more are in development. Although antibodies share certain structural similarities, development of commercially viable antibody pharmaceuticals has not been straightforward because of their unique and somewhat unpredictable solution behavior. This article… CONTINUE READING

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