Antibody responses to glycolipid-borne carbohydrates require CD4+ T cells but not CD1 or NKT cells.


Naturally occurring anti-carbohydrate antibodies play a major role in both the innate and adaptive immune responses. To elicit an anti-carbohydrate immune response, glycoproteins can be processed to glycopeptides and presented by the classical antigen-presenting molecules, major histocompatibility complex (MHC) Class I and II. In contrast, much less is… (More)
DOI: 10.1038/icb.2010.166


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