Antibody response to whole-virus and split-virus influenza vaccines in successful ageing.

@article{McElhaney1993AntibodyRT,
  title={Antibody response to whole-virus and split-virus influenza vaccines in successful ageing.},
  author={Janet E. McElhaney and Graydon S Meneilly and Kelly E Lechelt and Bonita Lynn Beattie and Robert Chris Bleackley},
  journal={Vaccine},
  year={1993},
  volume={11 10},
  pages={
          1055-60
        }
}
The antibody response to influenza vaccination has been variably reported to be decreased in elderly individuals. To determine the effect of ageing alone on this antibody response, a group of carefully-screened healthy elderly subjects were compared with young adult controls. Antibody titres for several strains of influenza were measured before and after vaccination with whole-virus (WVV) and split-virus influenza vaccines (SVV) in two successive years. In general, the antibody response to WVV… CONTINUE READING

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