Antibody response to the 45 kDa Candida albicans antigen in an animal model and potential role of the antigen in adherence.

Abstract

The Candida antigen CR3-RP (complement receptor 3-related protein) is supposed to be a 'mimicry' protein because of its ability to bind antibody directed against the alpha subunit of the mammalian CR3 (CD11b/CD18). This study aimed to (i) investigate the specific humoral isotypic response to immunization with CR3-RP in vivo in a rabbit animal model, and (ii… (More)
DOI: 10.1099/jmm.0.2008/001479-0

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