Antibody profiles for the diagnosis of antiphospholipid syndrome.

  title={Antibody profiles for the diagnosis of antiphospholipid syndrome.},
  author={Vittorio Pengo and Alessandra Biasiolo and Cinzia Pegoraro and Umberto Cucchini and Franco Noventa and Sabino Iliceto},
  journal={Thrombosis and haemostasis},
  volume={93 6},
Among the so called 'antiphospholipid antibodies', the presence of Lupus Anticoagulant (LA) is associated with thrombosis-related events and defines the antiphospholipid syndrome. The role of anti-cardiolipin (aCL) antibodies and anti-human beta2-glycoprotein I (abeta2GPI) antibodies is less striking. Since the problem of standardization for these tests is far from resolved, we evaluated whether the combination of results (antiphospholipid laboratory profiles) could help to better classify… CONTINUE READING