Antibody modified gold nano-mushroom arrays for rapid detection of alpha-fetoprotein.

  title={Antibody modified gold nano-mushroom arrays for rapid detection of alpha-fetoprotein.},
  author={Wanbo Li and Xueqin Jiang and Jiancai Xue and Zhangkai Zhou and Jianhua Zhou},
  journal={Biosensors & bioelectronics},
Localized surface plasmon resonance (LSPR) combined with immunoassay shows greatly potential in fast detection of tumor markers. In this paper, a highly sensitive LSPR substrate has been fabricated and modified for direct detection of alpha-fetoprotein (AFP). The biosensor was prepared by interference lithography, and modified by covalently immobilizing anti-AFP on the surface of gold nano-mushroom arrays (GNMA). The modification process was investigated by Vis-NIR reflectance spectra and… CONTINUE READING

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