Antibody mediated lung targeting of long-circulating emulsions.

  title={Antibody mediated lung targeting of long-circulating emulsions.},
  author={Young Kouk Song and Dijie Liu and Kazuo Maruyama and Tomoko Takizawa},
  journal={PDA journal of pharmaceutical science and technology},
  volume={50 6},
Monoclonal antibody 34A, which specifically binds to a surface glycoprotein (thrombomodulin) of the pulmonary endothelial cell surface in mice, has been conjugated to the surface of long-circulating emulsions composed of Castor oil, phosphatidylcholine and polyethylene glycol coupled to distearoylphosphatidyl-ethanolamine. These antibody-containing… CONTINUE READING