Antibody-mediated basophil accumulations in cutaneous hypersensitivity reactions of guinea pigs.

@article{Askenase1976AntibodymediatedBA,
  title={Antibody-mediated basophil accumulations in cutaneous hypersensitivity reactions of guinea pigs.},
  author={PhilipW. Askenase and J. David Haynes and Bruce Hayden},
  journal={Journal of immunology},
  year={1976},
  volume={117 1},
  pages={
          216-24
        }
}
Cutaneous basophil hypersensitivity (CBH) was studied in guinea pigs by using simplified histologic techniques. Animals immunized with oxazolone or picryl conjugates of keyhole limpet hemocyanin (KLH) emulsified with complete (CFA) or incomplete Freund's adjunvant (IFA) were found to have hapten-specific cutaneous basophil reactions when skin tested at 1 week with oxazolone or picryl chloride contant painting or intradermal injection of oxazolone or picryl-conjugated human serum albumin… CONTINUE READING

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