Antibody-dependent cell-mediated (K cell) cytotoxicity against isolated hepatocytes in chronic active hepatitis.

@article{Cochrane1976AntibodydependentC,
  title={Antibody-dependent cell-mediated (K cell) cytotoxicity against isolated hepatocytes in chronic active hepatitis.},
  author={Alan H. Cochrane and A Moussouros and A D Thomsom and Adrian L. W. F. Eddleston and R Wiiliams},
  journal={Lancet},
  year={1976},
  volume={1 7957},
  pages={441-4}
}
Lymphocytes from 12 of 17 patients with chronic active hepatitis were cytotoxic towards isolated hepatocytes in a microcytotoxicity assay. Enriched fractions of B cells, prepared by removal of E-rosetted cells, were cytotoxic in all 12 cases, whereas T-cell fractions, prepared by removal of erythrocyte-antibody-complement-rosetted cells, were cytotoxic in… CONTINUE READING