Antibody binding of circulating ergot alkaloids in cattle grazing tall fescue.

@article{Hill1994AntibodyBO,
  title={Antibody binding of circulating ergot alkaloids in cattle grazing tall fescue.},
  author={Nicholas S. Hill and Frederick N. Thompson and D. L. Dawe and John A. Stuedemann},
  journal={American journal of veterinary research},
  year={1994},
  volume={55 3},
  pages={419-24}
}
Direct evidence linking alkaloids found in endophyte-infected tall fescue forage with the livestock disorder known as fescue toxicosis is lacking. Physiologic effects of fescue toxicosis include reduced serum prolactin concentration in cattle. A monoclonal antibody specific to the lysergic moiety of ergot alkaloids was developed in mice after creating an immunogen by linking lysergol to human serum albumin. The antibody was specific to the lysergic moiety and, therefore, it cross-reacted with… CONTINUE READING

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