Antibody-based detection of ERG rearrangements in prostate core biopsies, including diagnostically challenging cases: ERG staining in prostate core biopsies.

Abstract

CONTEXT Fusions of androgen-regulated genes and v-ets erythroblastosis virus E26 oncogene homolog (avian) (ERG) occur in approximately 50% of prostate cancers, encoding a truncated ERG product. In prostatectomy specimens, ERG rearrangements are greater than 99% specific for prostate cancer or high-grade prostatic intraepithelial neoplasia adjacent to ERG… (More)
DOI: 10.5858/arpa.2011-0424-OA

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Cite this paper

@article{Tomlins2012AntibodybasedDO, title={Antibody-based detection of ERG rearrangements in prostate core biopsies, including diagnostically challenging cases: ERG staining in prostate core biopsies.}, author={Scott Arthur Tomlins and Nallasivam Palanisamy and Javed Zafar Siddiqui and Arul M. Chinnaiyan and Lakshmi Priya Kunju}, journal={Archives of pathology & laboratory medicine}, year={2012}, volume={136 8}, pages={935-46} }