Antibody based EpCAM targeted Therapy of Cancer, Review and update.

Abstract

Todays, after four decades of the discovery of monoclonal antibodies by Kohler and Milstein in 1975, a dozen of antibodies are used in cancer targeted therapy with different strategies. The success of these antibodies depends on the specificity of antigens expressed on the cancer cells. Epithelial cell adhesion molecule (EpCAM), a homophilic cell-cell… (More)
DOI: 10.2174/1568009618666180102102311

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