Antibody-antigen interactions : What is the required time to equilibrium ?

  title={Antibody-antigen interactions : What is the required time to equilibrium ?},
  author={Karl Andersson and Hanna Bj{\"o}rkelund and Magnus Malmqvist},
The use of antibodies is widespread in many areas including in-vivo and in-vitro diagnostics, quantitative analysis in research laboratories and as therapeutic substances. Since the methods for generation of antibodies has improved and regularly results in high-affinity interactions, the standard assays used for quantification of the interaction properties should be revisited because they do not necessarily produce accurate results. Here we show that in several cases, the affinity determination… CONTINUE READING

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