Antibody against pulmonary surfactant protein A recognizes proteins in intestine and swim bladder of the freshwater fish, carp.

@article{Rubio1996AntibodyAP,
  title={Antibody against pulmonary surfactant protein A recognizes proteins in intestine and swim bladder of the freshwater fish, carp.},
  author={Saioa Rubio and Bernadette Chailley-Heu and Robert A Ducroc and Jacques R. Bourbon},
  journal={Biochemical and biophysical research communications},
  year={1996},
  volume={225 3},
  pages={901-6}
}
An antibody raised against rat pulmonary surfactant protein A (SP-A) bound on Western blots to proteins present in intestinal mucosa and in swim bladder, but not in gills of the carp. The fish protein(s) revealed by the antibody exhibited an electrophoretical behavior similar to that of rat SP-A with a characteristic triplet in the 30- to 35-kDa range. It therefore appears that proteins immunologically very close to mammalian SP-A are present in modern fish which evolved from ancestors that… CONTINUE READING

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