Antibody Responses to Antigenic Determinants of Influenza Virus Hemagglutinin

@article{Virelizier1974AntibodyRT,
  title={Antibody Responses to Antigenic Determinants of Influenza Virus Hemagglutinin},
  author={Jean Louis Virelizier and Anthony C. Allison and Geoffrey C. Schild},
  journal={The Journal of Experimental Medicine},
  year={1974},
  volume={140},
  pages={1571 - 1578}
}
Mice immunized sequentially with two related influenza virus hemagglutinins (HA) produced a secondary antibody response with two different specificities. Some antibodies were specific for determinants common to both HA's. Paradoxically, some antibodies were directed to determinants existing only in the HA first encountered. Primed spleen cells treated with anti-theta serum and complement were transferred from animals immunized with the first HA to either normal, irradiated, or thymus-deprived… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 20 references

Immunological memory

  • A. J. S. Davies, R. L. Carter, N. A. Mitchison
  • Contemporary Topics in Immunology . II . Thymus…
  • 1973

Immunological memory. In Contemporary Topics in Immunology

  • Miller, P J.F.A.
  • 1973
1 Excerpt

Regulation of the immune response. II. Qualitative and quantitative differences between thymus and bone marrow-derived lymphocyte in the recognition of antigen

  • M. Hoffman, J. W. Kappler
  • J. Exp. Med
  • 1973
1 Excerpt

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