Antibodies to synthetic fragments of nucleophosmin for the specific detection of its monomeric and oligomeric forms

Abstract

Immunoactive fragments corresponding to the N-terminal (19–36) and C-terminal (283–294) regions of the NPM1.1 isoform of nucleophosmin and their shortened fragments were chosen and synthesized. Rabbits were immunized with free full-size peptides and their protein conjugates. Antibodies produced against the 19–36 and 283–294 peptides were purified by… (More)
DOI: 10.1134/S1068162009060077

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