Antibodies to surface epitopes of the carbohydrate larval antigen CarLA are associated with passive protection in strongylid nematode challenge infections.

@article{Harrison2008AntibodiesTS,
  title={Antibodies to surface epitopes of the carbohydrate larval antigen CarLA are associated with passive protection in strongylid nematode challenge infections.},
  author={Gavin Harrison and Helen Pulford and Elizabeth E Doolin and Anton Pernthaner and Charles B Shoemaker and Wayne R. Hein},
  journal={Parasite immunology},
  year={2008},
  volume={30 11-12},
  pages={
          577-84
        }
}
Sheep were immunized by multiple truncated infections with the gastrointestinal nematodes Trichostrongylus colubriformis, Haemonchus contortus and Teladorsagia circumcincta. Three infections with T. colubriformis of 14 days plus five booster doses of L3 stimulated highly effective protection against challenge (99%). Three infections of 14 days plus three booster doses with H. contortus also resulted in significant protection against challenge infection (87%), but the same procedure was not… CONTINUE READING
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