Antibodies to myelin oligodendrocyte glycoprotein in aquaporin 4 antibody seronegative longitudinally extensive transverse myelitis: Clinical and prognostic implications

@article{CoboCalvo2016AntibodiesTM,
  title={Antibodies to myelin oligodendrocyte glycoprotein in aquaporin 4 antibody seronegative longitudinally extensive transverse myelitis: Clinical and prognostic implications},
  author={A. Cobo-Calvo and M. Sep{\'u}lveda and Raphael Bernard-Valnet and A. Ruiz and D. Brassat and S. Mart{\'i}nez-Y{\'e}lamos and A. Saiz and R. Marignier},
  journal={Multiple Sclerosis Journal},
  year={2016},
  volume={22},
  pages={312 - 319}
}
  • A. Cobo-Calvo, M. Sepúlveda, +5 authors R. Marignier
  • Published 2016
  • Medicine
  • Multiple Sclerosis Journal
  • Objective: We aimed to investigate the frequency and clinical significance of antibodies to myelin oligodendrocyte glycoprotein (MOG-abs) in patients who presented with a first episode of seronegative aquaporin 4 antibody (AQP4-ab) longitudinally extensive transverse myelitis (LETM). Methods: Epidemiological, clinical, and paraclinical data of 56 patients from three European centres were analysed. Patients were retrospectively tested for MOG-abs and AQP4-abs, by cell-based assays. Findings… CONTINUE READING
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