Antibodies to mycobacteria in human tuberculosis. I. Development of antibodies before and after antimicrobial therapy.

@article{Kaplan1980AntibodiesTM,
  title={Antibodies to mycobacteria in human tuberculosis. I. Development of antibodies before and after antimicrobial therapy.},
  author={Michael Kaplan and Merrill W. Chase},
  journal={The Journal of infectious diseases},
  year={1980},
  volume={142 6},
  pages={
          825-34
        }
}
Circulating antibodies were detected before treatment in the serum of 18 of 40 patients with newly acquired tuberculosis and of eight of 12 patients with reactivated tuberculosis by microimmunodiffusion tests with unheated mycobacterial culture filtrate, arabinogalactan, arabinomannan, and a specific culture filtrate fraction. Some patients responded to a single antigen, while others responded to two and at times four or more. Some of these antibodies reacted with polysaccharides, but many… CONTINUE READING
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