Antibodies to anti-thymocyte globulin in aplastic anemia patients have a negative impact on hematopoietic SCT

Abstract

Severe aplastic anemia (SAA) is a life threatening BM failure and the preferred therapy for children is allogeneic hematopoietic SCT (HSCT) with an HLA-matched sibling donor. Immunosuppressive therapy with anti-thymocyte globulin (ATG) and CsA is an alternative for patients lacking an HLA-identical donor. For many years, horse ATG (hATG) was the preferred… (More)
DOI: 10.1038/bmt.2011.259

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