Antibodies to a trypsin sensitive pancreatic antigen in chronic inflammatory bowel disease: specific markers for a subgroup of patients with Crohn's disease.

@article{Seibold1991AntibodiesTA,
  title={Antibodies to a trypsin sensitive pancreatic antigen in chronic inflammatory bowel disease: specific markers for a subgroup of patients with Crohn's disease.},
  author={Frank W. Seibold and Peter Weber and H. Jenss and Karl Hermann Wiedmann},
  journal={Gut},
  year={1991},
  volume={32 10},
  pages={1192-7}
}
The presence of antibodies against pancreatic juice (PAB) in patients with Crohn's disease has recently been reported. In our study sera from 273 patients with inflammatory bowel disease (222 with Crohn's disease, 51 with ulcerative colitis) have been examined for PAB and also for antibodies against gut tissues by means of indirect immunofluorescence. PAB were found in 68 of the 222 patients with Crohn's disease (31%), with titres ranging from 1/10 to 1/1280, and in only two patients with… CONTINUE READING
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The role of the immune system in inflammatory bowel disease

  • RP MacDermott, WF Stenson
  • Immunology and Allergy Clinics ofNorth America
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