Antibodies to a scrapie prion protein

  title={Antibodies to a scrapie prion protein},
  author={Paul E. Bendheim and Ronald A. Barry and Stephen J. DeArmond and Daniel P. Stites and Stanley B Prusiner},
Scrapie is a slow infection of the nervous system which progresses in the absence of any apparent immune response1–8. The recent development of a large-scale purification protocol for scrapie prion9 made it possible to obtain substantial quantities of electrophoretically purified prion protein (PrP 27–30) and we report here on the successful production of a rabbit antiserum to PrP 27–30. The antiserum reacted with PrP 27–30 and several lower molecular weight proteins as shown by Western blots… CONTINUE READING

From This Paper

Topics from this paper.
46 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 46 extracted citations

Similar Papers

Loading similar papers…