Antibodies to Domain I of β(2)Glycoprotein I are in close relation to patients risk categories in Antiphospholipid Syndrome (APS).

@article{Banzato2011AntibodiesTD,
  title={Antibodies to Domain I of β(2)Glycoprotein I are in close relation to patients risk categories in Antiphospholipid Syndrome (APS).},
  author={Alessandra Banzato and Nicole Pozzi and R Frasson and Vincenzo De Filippis and Amelia Ruffatti and Elisa Bison and Seena Jose Padayattil and Gentian Denas and Vittorio Pengo},
  journal={Thrombosis research},
  year={2011},
  volume={128 6},
  pages={583-6}
}
INTRODUCTION Antiphospholipid Syndrome (APS) is characterized by the presence of circulating antiphospholipid antibodies in patients with thrombosis or pregnancy morbidity. Antibodies involved in these disorders are mainly those directed against β(2)-Glycoprotein I (β(2)GPI) with the major epitope apparently located on discontinuous antigen with several parts of Domain I (DmI) involved. The relation between anti-DmI antibodies and patients' risk categories is unknown. MATERIALS AND METHODS… CONTINUE READING

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