Antibodies to Borrelia burgdorferi OspA, OspC, OspF, and C6 antigens as markers for early and late infection in dogs.

@article{Wagner2012AntibodiesTB,
  title={Antibodies to Borrelia burgdorferi OspA, OspC, OspF, and C6 antigens as markers for early and late infection in dogs.},
  author={Bettina Wagner and Heather Freer and Alicia Rollins and David Garcia-Tapia and Hollis Nancy Erb and Christopher G Earnhart and R T Marconi and Patrick Meeus},
  journal={Clinical and vaccine immunology : CVI},
  year={2012},
  volume={19 4},
  pages={527-35}
}
Lyme disease in the United States is caused by Borrelia burgdorferi sensu stricto, which is transmitted to mammals by infected ticks. Borrelia spirochetes differentially express immunogenic outer surface proteins (Osp). Our aim was to evaluate antibody responses to Osp antigens to aid the diagnosis of early infection and the management of Lyme disease. We analyzed antibody responses during the first 3 months after the experimental infection of dogs using a novel multiplex assay. Results were… CONTINUE READING

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Borrelia spirochetes differentially express immunogenic outer surface proteins ( Osp ) .
Borrelia spirochetes differentially express immunogenic outer surface proteins ( Osp ) .
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