Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome

  title={Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome},
  author={M. Loebel and P. Grabowski and H. Heidecke and S. Bauer and L. Hanitsch and Kirsten Wittke and C. Meisel and P. Reinke and Hans-Dieter Volk and {\O}. Fluge and O. Mella and C. Scheibenbogen},
  journal={Brain, Behavior, and Immunity},
  • M. Loebel, P. Grabowski, +9 authors C. Scheibenbogen
  • Published 2016
  • Medicine
  • Brain, Behavior, and Immunity
  • Infection-triggered disease onset, chronic immune activation and autonomic dysregulation in CFS point to an autoimmune disease directed against neurotransmitter receptors. Autoantibodies against G-protein coupled receptors were shown to play a pathogenic role in several autoimmune diseases. Here, serum samples from a patient cohort from Berlin (n=268) and from Bergen with pre- and post-treatment samples from 25 patients treated within the KTS-2 rituximab trial were analysed for IgG against… CONTINUE READING
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