• Biology
  • Published 2008

Antibodies specific to pro-angiogenic isoform of vascular endothelial growth factor (the vegf)

@inproceedings{2008AntibodiesST,
  title={Antibodies specific to pro-angiogenic isoform of vascular endothelial growth factor (the vegf)},
  author={メナチェム ゼーヴィ and スティーブン ジェイ. ハーパー, and デイビッド オー. ベイツ, and ミリアム ワイ. マンゲラス,},
  year={2008}
}
The present invention provides antibodies, as well as molecules having at least the antigen-binding portion of an antibody, against agonist pro-angiogenic, pro-permeability, vasodilatory isoforms of VEGF. Disclosed antibodies and antibody fragments are characterized by being capable of binding to and neutralizing pro-angiogenic forms of VEGF while not effecting isoforms of VEGF which are anti angiogenic. Methods of production and use in therapy and diagnosis, of such antibodies and antibody… CONTINUE READING