Antibodies reactive with C-terminus of the second conserved region of HIV-1gp120 as possible prognostic marker and therapeutic agent for HIV disease.

@article{Veljkovic2004AntibodiesRW,
  title={Antibodies reactive with C-terminus of the second conserved region of HIV-1gp120 as possible prognostic marker and therapeutic agent for HIV disease.},
  author={Nevena Veljkovic and Donald R Branch and Radmila M Metlas and Jelena Prljic and Roberto Manfredi and William W. Stringer and Veljko Veljkovic},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2004},
  volume={31 Suppl 1},
  pages={S39-44}
}
It has been reported that antibodies reactive with peptide RSANFTDNAKTIIVQLNQSVEIN (peptide NTM) derived from the C-terminus of the second conserved domain of HIV-1 envelope glycoprotein gp120 could represent an important factor in control of the HIV disease. In order to check this notion we (i) tested reactivity with peptide NTM serum samples collected from 310 consecutive HIV-1 infected patients with a CD4(+) lymphocyte count ranging from 10 to 800/microL and (ii) performed the longitudinal… CONTINUE READING