Antibodies reactive to non-HLA antigens in transplant glomerulopathy.

@article{Dinavahi2011AntibodiesRT,
  title={Antibodies reactive to non-HLA antigens in transplant glomerulopathy.},
  author={Rajani V Dinavahi and Ajish George and Anne Tretin and Enver Akalin and Scott Ames and Jonathan S. Bromberg and Graciela Deboccardo and Nicholas Dipaola and Susan M Lerner and Anita Mehrotra and Barbara T Murphy and Tibor Nadasdy and Estela Paz-Artal and Daniel R. Salomon and Bernd Schr{\"o}ppel and Vinita Sehgal and Ravi Sachidanandam and Peter S Heeger},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2011},
  volume={22 6},
  pages={1168-78}
}
Although T and B cell alloimmunity contribute to transplant injury, autoimmunity directed at kidney-expressed, non-HLA antigens may also participate. Because the specificity, prevalence, and importance of antibodies to non-HLA antigens in late allograft injury are poorly characterized, we used a protein microarray to compare antibody repertoires in pre- and post-transplant sera from several cohorts of patients with and without transplant glomerulopathy. Transplantation routinely induced changes… CONTINUE READING
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