Antibodies reacting to mimotopes of Simian virus 40 large T antigen, the viral oncoprotein, in sera from children

  title={Antibodies reacting to mimotopes of Simian virus 40 large T antigen, the viral oncoprotein, in sera from children},
  author={Elisa Mazzoni and Francesca Frontini and John Charles Rotondo and Nunzia Zanotta and Arianna Fioravanti and Francesca Minelli and Elena Torreggiani and Giuseppina Campisciano and Annalisa Marcuzzi and Giovanni Guerra and Alberto Tommasini and Antoine Touz{\'e} and Fernanda Martini and Mauro Tognon and Manola Comar},
  journal={Journal of Cellular Physiology},
  pages={3170 - 3179}
Recent data indicate that the Simian virus 40 (SV40) infection appears to be transmitted in humans independently from early SV40‐contaminated antipolio vaccines. Serum antibodies against SV40 large T antigen (Tag) were analyzed in children/adolescents and young adults. To investigate antibodies reacting to SV40 Tag antigens, serum samples ( n = 812) from children and young adults were analyzed by indirect ELISAs using specific SV40 Tag mimotopes. Mimotopes were synthetic peptides corresponding… Expand
3 Citations
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Specific Antibodies Reacting with SV40 Large T Antigen Mimotopes in Serum Samples of Healthy Subjects
A novel ELISA with two mimotopes of the early viral regions is able to detect in a specific manner Simian Virus 40 large T antigen-antibody responses. Expand
Serological Evidence of an Early Seroconversion to Simian Virus 40 in Healthy Children and Adolescents
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High prevalence of antibodies reacting to mimotopes of Simian virus 40 large T antigen, the oncoprotein, in serum samples of patients affected by non-Hodgkin lymphoma
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