Antibodies in action: role of human opsonins in killing Salmonella enterica serovar Typhi.


Although vaccines have been available for over a century, a correlate of protection for typhoid fever has yet to be identified. Antibodies are produced in response to typhoid infection and vaccination and are generally used as the gold standard for determining vaccine immunogenicity, even though their role in clearance of Salmonella enterica serovar Typhi… (More)
DOI: 10.1128/IAI.05081-11