Antibodies directed against ribosomal P proteins cross-react with phospholipids.

  title={Antibodies directed against ribosomal P proteins cross-react with phospholipids.},
  author={Laura Caponi and Consuelo Anzilotti and Giovanni Longombardo and Paola Migliorini},
  journal={Clinical and experimental immunology},
  volume={150 1},
Anti-ribosomal P protein (anti-P) antibodies are marker antibodies in systemic lupus erythematosus (SLE). Their association with psychiatric or neurological manifestations has been proposed, but remains controversial. Anti-phospholipid antibodies are the hallmark of a syndrome that may comprise a number of neurological manifestations. Thus, anti-P and anti-phospholipid antibodies have both been associated with central nervous system involvement and their co-existence in the same sera was… CONTINUE READING