Antibodies and neuronal autoimmune disorders of the CNS

@article{Graus2009AntibodiesAN,
  title={Antibodies and neuronal autoimmune disorders of the CNS},
  author={Francesc Graus and Albert Saiz and Josep Dalmau},
  journal={Journal of Neurology},
  year={2009},
  volume={257},
  pages={509-517}
}
We review the neuronal antibodies described in CNS disorders in order to clarify their diagnostic value, emphasize potentials pitfalls and limitations in the diagnosis of paraneoplastic neurological syndromes (PNS), and examine the current evidence for a possible pathogenic role. We propose to classify the neuronal antibodies associated with syndromes resulting from CNS neuronal dysfunction into two groups according to the location of the antigen: inside the neuron or in the cell membrane… 

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  • K. Bürk
  • Biology, Medicine
    Biomolecular concepts
  • 2011
The review gives an overview of the common characteristics of each group and provides more detailed information on single abs and the associated clinical syndromes.
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