Antibodies and Genetically Engineered Related Molecules: Production and Purification

@article{Roque2004AntibodiesAG,
  title={Antibodies and Genetically Engineered Related Molecules: Production and Purification},
  author={A. Roque and C. Lowe and M. A. Taipa},
  journal={Biotechnology Progress},
  year={2004},
  volume={20}
}
Antibodies and antibody derivatives constitute 20 % of biopharmaceutical products currently in development, and despite early failures of murine products, chimeric and humanized monoclonal antibodies are now viable therapeutics. A number of genetically engineered antibody constructions have emerged, including molecular hybrids or chimeras that can deliver a powerful toxin to a target such as a tumor cell. However, the general use in clinical practice of antibody therapeutics is dependent not… Expand
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