Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein.

@article{Martin1993AntibodiesAT,
  title={Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein.},
  author={Heiko Martin and Yasmina Patel and David A Jones and Steven A. Howell and Katherine A. Robinson and Alastair Aitken},
  journal={FEBS letters},
  year={1993},
  volume={336 1},
  pages={189}
}
14-3-3 proteins are apparently ubiquitous eukaryotic proteins that comprise a large number of isoforms. They have been implicated in the regulation of a wide range of biological processes [reviewed in Aitken et al. (1992) Trends Biochem. Sci. 17, 498-501]. We have raised specific antibodies against each mammalian brain isoform of 14-3-3 employing peptides synthesised from the amino-terminal regions. The peptides were, like the proteins from mammalian brain, N-acetylated. The antiserum specific… CONTINUE READING