Antibodies against p53 are associated with poor prognosis of colorectal cancer.

@article{Houbiers1995AntibodiesAP,
  title={Antibodies against p53 are associated with poor prognosis of colorectal cancer.},
  author={Jos G. A. Houbiers and Sjoerd H. van der Burg and L van de Watering and Rob A. E. M. Tollenaar and Anneke Brand and Cornelius J H van de Velde and Cornelis J. M. Melief},
  journal={British Journal of Cancer},
  year={1995},
  volume={72},
  pages={637 - 641}
}
Mutation of the p53 gene is a common event in colorectal cancer. This alteration can result in cellular accumulation of p53 and may also induce p53 antibodies. Accumulation of p53 in tumour cells has been associated with poor prognosis of colorectal cancer. We tested preoperative sera from 255 patients with colorectal cancer by enzyme-linked immunosorbent… CONTINUE READING