Antibiotics modulate vaccine-induced humoral immune response.

  title={Antibiotics modulate vaccine-induced humoral immune response.},
  author={Patrick C Y Woo and Hoi Wah Tsoi and Li Ping Wong and Hoi Chung Leung and K. Y. Yuen},
  journal={Clinical and diagnostic laboratory immunology},
  volume={6 6},
The effects of antibiotics on the antigen-specific humoral immune response are not known. Macrolides, tetracyclines, and beta-lactams are commonly prescribed antibiotics. The first two are known to have immunomodulatory activities. The effects of clarithromycin, doxycycline, and ampicillin on the primary and secondary antibody responses to tetanus toxoid, a pneumococcal polysaccharide vaccine, a hepatitis B virus surface antigen (HBsAg) vaccine, and live attenuated Salmonella typhi (Ty21a) were… CONTINUE READING