Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease.

@article{Dejaco2003AntibioticsAA,
  title={Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease.},
  author={Clemens Dejaco and Marieluise Harrer and Thomas Waldhoer and Wolfgang Miehsler and Harald Vogelsang and Walter Reinisch},
  journal={Alimentary pharmacology & therapeutics},
  year={2003},
  volume={18 11-12},
  pages={1113-20}
}
BACKGROUND Antibiotics and thiopurines have been employed in the management of fistulizing Crohn's disease, although evidence of their efficacy is rare. AIM To evaluate, in a prospective, open-label study, the influence of antibiotics and azathioprine on the clinical outcome of perianal fistulas in patients with Crohn's disease. METHODS Fifty-two patients entered the study, starting with an 8-week regimen of ciprofloxacin (500-1000 mg/day) and/or metronidazole (1000-1500 mg/day). Seventeen… CONTINUE READING

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